CD7 (EP132) Antibody (Rabbit Monoclonal) Highly Specific Detection of T-Cell and NK Cell Marker CD7 for Hematopathology and Immunophenotyping The CD7 (EP132) Rabbit Monoclonal Antibody is a high-affinity, recombinant antibody designed for the specific detection of CD7, a 40 kDa transmembrane glycoprotein expressed on the majority of peripheral T cells, natural killer (NK) cells, and early thymocytes. CD7 plays a key role in T-cell activation and interaction, making it a crucial biomarker for T-cell lineage identification and hematologic malignancy diagnosis. Clone EP132 is engineered for enhanced sensitivity and specificity, delivering consistent, clean membranous staining with minimal background noise. This antibody is extensively validated for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) tissues, and is also suitable for flow cytometry (FC) and Western blotting (WB). It is a powerful tool for identifying CD7 expression in T-cell leukemias, T-cell lymphomas, acute lymphoblastic leukemia (ALL), and related disorders. In diagnostic pathology, CD7 is frequently used to confirm T-cell lineage in cases where immunophenotypic profiles are ambiguous. It is particularly useful in differentiating between T- and B-cell neoplasms and in evaluating loss or aberrant expression patterns commonly seen in T-cell malignancies. Manufactured with advanced recombinant technology and affinity-purified for optimal performance, the CD7 (EP132) Rabbit Monoclonal Antibody ensures reproducible, high-quality results with strong diagnostic and research utility. Key Features: Clone: EP132 Host / Isotype: Rabbit / IgG Target: CD7 (Cluster of Differentiation 7) Reactivity: Human Applications: Immunohistochemistry (IHC), Flow Cytometry (FC), Western Blot (WB) Sample Types: FFPE tissues, frozen sections, blood samples, cell lysates Purification: Affinity-purified Storage: Store at −20°C; avoid repeated freeze-thaw cycles Applications in Research & Diagnostics: Immunophenotyping of T cells and NK cells Diagnosis of T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphomas Characterization of hematopoietic malignancies Evaluation of immune cell populations in tissue samples Basic and translational immunology research
Humans; others not tested
Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Buffer with protein carrier and preservative
Store at 2ºC to 8ºC
Tonsil or lymph node
Membrane
IgG
Recombinant fragment (around aa 72-175) of human CD7 protein
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
