The CD79a Monoclonal Antibody [Clone HM47/A9] is a mouse monoclonal antibody targeting CD79a, a transmembrane protein associated with the B-cell receptor (BCR) complex. CD79a is expressed from the early pro-B cell stage through to plasma cells, making it a robust marker for identifying B-cell lineage in hematopathology. This clone is ideal for immunohistochemistry on formalin-fixed, paraffin-embedded (FFPE) tissues, offering reliable membranous and cytoplasmic staining in B cells and B-cell derived malignancies.
Mouse
A synthetic peptide corresponding to aa 202-216 (GTYQDVGSLNIADVQ) of human CD79a protein.
HM47/A9
IgG1, kappa
Human, Monkey, Pig, Cow, Mouse and Rat. Others not known.
Daudi or Ramos cells. Germinal center B-cells in a lymph node or tonsil.
Anti-CD79a is generally used to complement anti-CD20 especially for mature B-cell lymphomas after treatment with Rituximab (anti-CD20).
Cell surface