The CD8 Antibody (Clone C8/144B) is a high-affinity mouse monoclonal antibody developed for the specific detection of CD8, a surface glycoprotein expressed on cytotoxic T lymphocytes (CD8+ T-cells). This antibody is widely used in immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) tissues, making it an essential marker in both diagnostic pathology and immunology research. Clone C8/144B binds specifically to the CD8α chain, providing robust membranous staining of CD8+ T-cells with minimal background. It is particularly valuable in the evaluation of tumor-infiltrating lymphocytes (TILs), immune profiling, and the differential diagnosis of T-cell lymphomas and immune-related disorders. This antibody is frequently included in IHC panels for solid tumors, lymphoid neoplasms, and organ transplant pathology. Validated for use on manual and automated IHC platforms, this antibody is available in both concentrated and ready-to-use formats. It offers excellent specificity, consistent staining, and lot-to-lot reliability, making it a trusted tool for both high-throughput diagnostic laboratories and academic research centers. Key Features: Clone: C8/144B Host Species: Mouse Monoclonal Target Antigen: CD8 (CD8α chain) Applications: Immunohistochemistry (IHC) on FFPE tissues Cellular Localization: Membranous Species Reactivity: Human Formulations: Concentrated and ready-to-use Use Cases: T-cell immunophenotyping, tumor-infiltrating lymphocyte analysis, T-cell lymphoma diagnostics Platform Compatibility: Compatible with both manual and automated IHC systems Quality Control: Batch-tested for specificity, sensitivity, and reproducibility The CD8 (C8/144B) Antibody is a critical reagent for identifying cytotoxic T-cells and assessing immune responses in tissue samples. Its high specificity and sensitivity make it ideal for research and clinical applications in oncology, transplant pathology, and autoimmune disease studies.
Humans; others not tested
Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Buffer with protein carrier and preservative
Store at 2ºC to 8ºC
Acute rejected kidney transplant
Membrane or cytoplasmic
IgG1 /κ
Recombinant full-length human complement cd5 protein
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
