The CD81 (TAPA-1) Monoclonal Antibody [Clone 1.3.3.22] is a high-affinity mouse monoclonal antibody directed against CD81, a member of the tetraspanin family. CD81 is broadly expressed on various hematopoietic and non-hematopoietic cells, including T cells, B cells, NK cells, dendritic cells, and epithelial cells. CD81 plays a key role in cell adhesion, signal transduction, T-cell activation, and B-cell development. It is also recognized as a co-receptor for Hepatitis C virus (HCV) entry, making it a relevant marker in both immune profiling and infectious disease research.
Mouse
Recombinant full-length human CD81 protein
1.3.3.22
IgG1 / Kappa
Human, Mouse, Rat
Daudi or Jurkat cells. Human lymphocytes. Human tonsil or liver., MCF-7, Ramos
Recognizes a protein of 26kDa, identified as CD81 (Workshop VI; Code CD81.1)).
Basolateral cell membrane, Cell membrane