The CDX2 antibody [EP25] is a monoclonal antibody that targets CDX2, a transcription factor critical for the development and maintenance of the intestinal epithelium. CDX2 is predominantly expressed in the nuclei of enterocytes and is essential for the differentiation of intestinal epithelial cells. The [EP25] clone is widely used in immunohistochemistry (IHC) to identify intestinal epithelial differentiation and to help diagnose gastrointestinal tumors, particularly colorectal adenocarcinomas. CDX2 expression is often used as a marker to distinguish intestinal-type tumors from other types of cancers. Additionally, CDX2 is valuable in assessing intestinal metaplasia and other pathological conditions involving the gastrointestinal tract. This antibody plays an important role in both research and clinical diagnostics, particularly in oncology and pathology.
Rabbit
EP25
IgG
IHC-P
Human
Store at 4ºC.
A synthetic peptide corresponding to residues near the C-term of human CDX-2 protein
Nuclear