CEA Antibody (Carcinoembryonic antigen)

CEA Antibody (Carcinoembryonic antigen)

CEA Antibody (Mouse Monoclonal) – Clone CEA31: Reliable Detection of Carcinoembryonic Antigen in Tumor Diagnostics The CEA Antibody (Mouse Monoclonal), Clone CEA31, is a highly specific and sensitive monoclonal antibody designed to detect Carcinoembryonic Antigen (CEA), a well-established tumor-associated glycoprotein frequently overexpressed in a wide range of epithelial cancers, including colorectal, gastric, pancreatic, lung, and breast carcinomas. This antibody is validated for use in immunohistochemistry (IHC) on formalin-fixed paraffin-embedded (FFPE) tissues, providing strong membranous and cytoplasmic staining of CEA-expressing tumor cells. Clone CEA31 delivers reliable, consistent performance in diagnostic and research applications and is widely used by pathologists to support the differential diagnosis of malignant tumors and to evaluate the origin of metastatic adenocarcinomas. Its high specificity for CEA makes it an essential marker in tumor profiling panels, particularly when distinguishing carcinomas of gastrointestinal origin from non-CEA-expressing neoplasms. 🔬 Applications and Clinical Utility: Colorectal Cancer Detection: CEA is a key marker in identifying primary and metastatic colorectal adenocarcinomas. Gastrointestinal and Pancreatic Tumors: Frequently expressed in gastric, pancreatic, and esophageal carcinomas. Lung and Breast Carcinomas: Assists in detecting CEA-positive lung adenocarcinomas and certain breast cancers. Tumor Origin Identification: Supports identification of carcinoma in cases of metastatic tumors of unknown primary. Research on Tumor Progression and Metastasis: Useful in cancer biology studies involving epithelial cell adhesion and tumor invasion mechanisms.