The CFTR (Clone CFTR/1342) Mouse Monoclonal Antibody is designed for the specific detection of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein, a chloride channel protein that is essential for maintaining proper fluid transport across epithelial surfaces. This antibody recognizes an epitope on the CFTR protein and is validated for IHC in formalin-fixed, paraffin-embedded (FFPE) tissues and Western blotting. CFTR/1342 provides clear apical membrane staining in epithelial tissues and is particularly useful for research into cystic fibrosis, epithelial ion transport regulation, and cancer biology.
Mouse
Recombinant human full-length CFTR
CFTR/1342
IgG1
Reacts with human. Others not known.
MOLT-4 cells. Pancreas, Kidney or Placenta.
Recognizes a protein of 165-170kDa, identified as cystic fibrosis transmembrane conductance regulator (CFTR).
Cell surface and Cytoplasmic.