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cGMP Antibody (Rabbit Monoclonal)

cGMP Antibody (Rabbit Monoclonal) – Precise Detection of Cyclic GMP in Signal Transduction and Cell Signaling Research The cGMP Antibody (Rabbit Monoclonal) is a high-affinity antibody specifically designed to detect cyclic guanosine monophosphate (cGMP), a key second messenger molecule involved in a wide range of physiological processes. This rabbit monoclonal antibody offers exceptional sensitivity and specificity for identifying cGMP in tissues and cells, making it ideal for applications in immunohistochemistry (IHC), immunocytochemistry (ICC), and signal transduction research. cGMP is a crucial regulator in multiple biological pathways, including nitric oxide (NO) signaling, vasodilation, phototransduction, cardiac function, and renal physiology. Its levels are tightly controlled by guanylate cyclases and phosphodiesterases. The cGMP Antibody is an indispensable tool for researchers studying cellular responses to NO, natriuretic peptides, and pharmacological agents that affect cyclic nucleotide pathways. 🔬 Key Applications: Signal Transduction Studies: Detects intracellular cGMP changes in response to nitric oxide or natriuretic peptides. Cardiovascular and Renal Research: Useful in studying vasodilation, hypertension, and diuretic mechanisms. Neuroscience and Sensory Biology: Applied in visual and olfactory signal transduction research. IHC/ICC: Detects cGMP localization and expression in formalin-fixed paraffin-embedded (FFPE) tissues or cultured cells. Pharmacological Research: Ideal for monitoring effects of PDE inhibitors and guanylate cyclase activators.

Specifications

Clone Name

RM467

Specificity

RM467 reacts to cGMP (Cyclic Guanosine Monophosphate). No cross reactivity with other cyclic nucleotide or nucleoside phosphate.

Immunogen

KLH-conjugated cGMP

Application

ELISA

Conjugate

None

Intended Use

Research Use Only

Storage and Stability

Stable for 1 Year at -20.0°C from date of receipt.

Isotype

Rabbit IgG

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G1359RP