The Chromogranin A (Clone A3) Mouse Monoclonal Antibody is specifically developed to detect Chromogranin A (CgA), a key marker of neuroendocrine differentiation. This antibody recognizes a cytoplasmic antigen expressed in neuroendocrine cells and tumors, providing strong and specific staining ideal for diagnostic and research purposes. Clone A3 offers excellent performance in immunohistochemistry on formalin-fixed, paraffin-embedded (FFPE) tissues and Western blot analysis, making it a trusted tool in the identification of neuroendocrine tumors including carcinoids, pheochromocytomas, and medullary thyroid carcinomas.
Mouse Monoclonal
BALB/C mice were immunized with purified C-terminal half of chromogranin.
A3
IgG2b,k
Human
Chromogranin A is a 439 amino acid protein present in secretory granules of a wide variety of endocrine cells and neurons.
Immunohistochemistry (IHC – FFPE), Western Blot (WB)
Cytoplasmic granular staining