Chromogranin A (CgA) Antibody – Rabbit Monoclonal for Reliable Neuroendocrine Tumor Detection The Chromogranin A (CgA) Rabbit Monoclonal Antibody is a highly specific and sensitive tool for the detection of Chromogranin A, a key glycoprotein found in the secretory granules of neuroendocrine cells. This antibody is extensively validated for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) tissues and is widely used in the diagnosis of neuroendocrine tumors (NETs) such as carcinoid tumors, pheochromocytomas, neuroblastomas, and medullary thyroid carcinomas. Chromogranin A serves as one of the most reliable markers for neuroendocrine differentiation. This rabbit monoclonal antibody provides strong cytoplasmic staining with minimal background, making it ideal for routine diagnostic use in surgical pathology and research applications. It plays a vital role in confirming neuroendocrine lineage, especially when used alongside other markers such as synaptophysin and CD56. 🔬 Clinical and Research Applications: Neuroendocrine Tumor Identification: Detects CgA in carcinoid tumors, small cell carcinomas, pheochromocytomas, and other NETs. Tumor Differentiation: Assists in confirming neuroendocrine origin in ambiguous or poorly differentiated tumors. Diagnostic IHC Panels: Often used in conjunction with synaptophysin, NSE, and CD56 for comprehensive NET evaluation. Research Use: Supports studies in neuroendocrine function, secretory granule biology, and tumor marker expression. Antibody Type: Rabbit Monoclonal Target Protein: Chromogranin A (CgA) Reactivity: Human (validated); cross-reactivity with some animal species possible Localization: Cytoplasmic staining in neuroendocrine cells and tumors Applications: Immunohistochemistry (IHC) on FFPE tissues Immunocytochemistry (ICC) Possible use in ELISA or Western blot with validation
GRM385
GRM385 reacts to Chromogranin A (CgA)
A peptide corresponding to the N-terminus of human Chromogranin A
Immunohistochemistry (IHC) Western Blot (WB)
Human
None
Research Use Only
Stable for 1 Year at -20.0°C from date of receipt.
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
