Product Overview

Chromogranin A (CHGA) (Neuroendocrine Marker); Polyclonal (Concentrate) is a polyclonal antibody developed to detect Chromogranin A, a secretory protein extensively expressed in neuroendocrine cells and neuroendocrine tumors. This antibody provides robust cytoplasmic staining in formalin-fixed, paraffin-embedded (FFPE) tissue sections, making it a reliable marker for identifying neuroendocrine differentiation across a wide range of tissues. Chromogranin A is involved in the formation of secretory granules and serves as a key biomarker for neuroendocrine tumors such as carcinoid tumors, pheochromocytomas, and small cell lung carcinoma. The concentrated format offers flexibility for dilution and optimization to accommodate various immunohistochemical protocols. Due to its broad reactivity and strong staining characteristics, the polyclonal Chromogranin A antibody is widely used in both diagnostic pathology and research to assess neuroendocrine tumor presence and differentiation.

Specifications

Species

Rabbit.

Immunogen

Recombinant human full-length Chromogranin A protein.

Clone

Polyclonal.

Isotype

IgG, kappa

Species Reactivity

Human. Does not react with rat. Others not known.

Positive Control

PC12 cells. Adrenal gland, bowel, parathyroid, pancreas, or pheochromocytoma.

Specificity

Recognizes the Chromogranin A protein.

Cellular Localization

Finely granular cytoplasmic

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G0518RP