Chromogranin A (CHGA) (Neuroendocrine Marker); Clone CHGA/765 (Concentrate) is a monoclonal antibody specifically developed to detect Chromogranin A, a key protein located in the secretory granules of neuroendocrine cells. Clone CHGA/765 provides strong and specific cytoplasmic staining in formalin-fixed, paraffin-embedded (FFPE) tissue sections, making it a valuable tool for the immunohistochemical identification of neuroendocrine differentiation. Chromogranin A is widely expressed in neuroendocrine tumors such as carcinoids, pheochromocytomas, paragangliomas, pancreatic neuroendocrine tumors, and small cell carcinomas. This antibody is particularly useful in differentiating neuroendocrine tumors from non-neuroendocrine neoplasms, aiding in accurate tumor classification and diagnosis. The concentrated format of Clone CHGA/765 allows for flexible protocol optimization and dilution according to laboratory needs. With its high sensitivity and specificity, this antibody is an essential reagent for both diagnostic pathology and neuroendocrine tumor research.
Mouse
Recombinant human CHGA protein
CHGA/765
IgG1, kappa
Human. Others not known.
PC12 cells. Adrenal gland, bowel, thyroid, pancreas, or pheochromocytoma.
Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets.
Finely granular cytoplasmic