Chromogranin A (CHGA) (Neuroendocrine Marker); Clone CHGA/798 (Concentrate) is a monoclonal antibody specifically engineered to detect Chromogranin A, a key acidic glycoprotein found in the secretory granules of neuroendocrine cells. Clone CHGA/798 provides strong, specific cytoplasmic staining in formalin-fixed, paraffin-embedded (FFPE) tissue sections, making it an essential tool for identifying neuroendocrine differentiation in both normal and neoplastic tissues. Chromogranin A is a well-established marker for a variety of neuroendocrine tumors, including carcinoid tumors, pheochromocytomas, pancreatic neuroendocrine tumors, and small cell lung carcinomas. This antibody is especially useful in distinguishing neuroendocrine neoplasms from non-neuroendocrine tumors, aiding in accurate diagnosis and tumor classification. Offered in a concentrated format, Clone CHGA/798 allows for flexible dilution and optimization based on specific laboratory protocols. Its high sensitivity and specificity make it a valuable asset in both clinical pathology and research settings focused on neuroendocrine tumor biology.
Mouse
Recombinant human CHGA protein
CHGA/798
IgG1, kappa
Human. Others not known.
PC12 cells. Adrenal gland, bowel, thyroid, pancreas, or pheochromocytoma.
Chromogranin A is present in neuroendocrine cells throughout the body, including the neuroendocrine cells of the large and small intestine, adrenal medulla and pancreatic islets.
Finely granular cytoplasmic