The Chromogranin A antibody [LK2H10] is a mouse monoclonal antibody specifically designed to detect Chromogranin A (CgA), a protein commonly found in the secretory granules of neuroendocrine cells. This antibody is widely used in both research and clinical settings, particularly in the immunohistochemical identification of neuroendocrine tumors such as pheochromocytomas, carcinoids, and neuroendocrine carcinomas. The LK2H10 clone offers high specificity and sensitivity, making it a reliable tool for diagnostic pathology. It is suitable for applications such as immunohistochemistry (IHC), where it enables the visualization of CgA expression in formalin-fixed, paraffin-embedded tissue sections. Its ability to selectively bind to human CgA allows for accurate detection of neuroendocrine differentiation in various tissue samples.
Mouse
LK2H10
IgG1
~68-75 kDa
~68-75 kDa
Human, Monkey, Pig, Mouse and Rat. Does not react with Guinea Pig, Sheep & Rabbit. Others not known.
Human pheochromocytoma
Finely granular cytoplasmic