The Chromogranin A Antibody (Clone LK2H10) is a high-affinity mouse monoclonal antibody specifically designed for the sensitive and specific detection of Chromogranin A, a key neuroendocrine secretory protein. Widely used in immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) tissues, this antibody is an essential marker in the identification and classification of neuroendocrine tumors, including those of the pancreas, lung, gastrointestinal tract, and adrenal gland. Clone LK2H10 delivers robust, reproducible staining patterns with strong cytoplasmic localization in neuroendocrine cells, making it a valuable diagnostic tool for pathologists and clinical laboratories. It is routinely employed in differentiating neuroendocrine neoplasms from non-neuroendocrine tumors, especially in complex histopathological evaluations. Validated for use in both manual and automated IHC platforms, the LK2H10 antibody is available in both concentrated and ready-to-use formats, making it a flexible choice for high-throughput labs and research institutions alike. It provides excellent specificity and minimal background, ensuring consistent results across tissue types and experimental conditions. Whether you're working in clinical diagnostics or translational cancer research, the Chromogranin A (LK2H10) antibody is a trusted marker for the accurate detection of neuroendocrine lineage and tumor characterization. Key Features: Clone: LK2H10 Host Species: Mouse Target Protein: Chromogranin A Applications: IHC (FFPE) Localization: Cytoplasmic Species Reactivity: Human Diagnostic Use: Neuroendocrine tumors, carcinoid tumors, pheochromocytoma, pancreatic NETs Formulation: Concentrated and ready-to-use formats available Compatibility: Manual and automated IHC platforms Quality Control: Batch-tested for consistent performance Applications in Research & Diagnostics: Neuroendocrine tumor identification Tumor grading and classification Differentiation of carcinoid tumors and small cell carcinomas Endocrine system and secretory cell studies
mouse
IgG
Affinity purification
Store at -20℃. Avoid freeze / thaw cycles.
80kDa
51kDa
SMab Recombinant Monoclonal Antibody
WB,IHC-P,IF/ICC,ELISA
Human,Mouse,Rat
LK2H10
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Chromogranin A (P10645).
Chromaffin granule, extracellular region, extracellular space, perinuclear region of cytoplasm.
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
