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Product Overview

Clone: OV-TL12-30

CK7, Clone OV-TL12/30 is a monoclonal antibody specifically designed to detect Cytokeratin 7, an intermediate filament protein expressed in the simple epithelia lining the glandular and transitional tissues. Clone OV-TL12/30 provides strong and specific cytoplasmic staining in formalin-fixed, paraffin-embedded (FFPE) tissue sections, making it a widely used marker in immunohistochemistry for identifying epithelial origin and differentiation. CK7 is commonly expressed in various carcinomas, including those of the lung, breast, ovary, and urinary tract, and its detection helps distinguish these tumors from CK7-negative malignancies. Clone OV-TL12/30 is particularly valuable in diagnostic pathology for tumor classification, aiding in the differentiation of primary versus metastatic lesions. The antibody’s reliable staining pattern and high specificity make it an essential tool in both clinical diagnostics and research applications.

Specifications

Species

Mouse

Immunogen

OTN 11, ovarian carcinoma cell line

Clone

OV-TL12/30

Isotype

IgG1

Specificity

The 55 kDa intermediate filament protein (IFP) that this antibody detects is known as cytokeratin 7. This antibody exhibits no cross-reaction with other IFPs and is very specific to cytokeratin 7.

SPECIES REACTIVITY

Human; Others not known.

POSITIVE CONTROL

HeLa cells. Carcinoma of ovary, lung, cervix, or breast. Cellular Localization: Cytoplasmic

CELLULAR LOCALIZATION

Cytoplasmic.

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G00142RP