The CK5 (Cytokeratin-5) Rabbit Monoclonal Antibody, Clone EP1601Y, is a high-affinity, highly specific antibody designed for the immunohistochemical detection of cytokeratin-5, a type II intermediate filament protein found in the basal layer of stratified squamous epithelium and various epithelial-derived tumors. This antibody is widely used in cancer diagnostics, particularly for identifying basal-like breast carcinomas, squamous cell carcinomas, and other epithelial malignancies. Clone EP1601Y offers robust cytoplasmic staining with minimal background, making it ideal for use on formalin-fixed, paraffin-embedded (FFPE) tissue sections in IHC applications. Its strong and specific reactivity with basal epithelial cells and tumor tissues supports accurate diagnosis, tumor subtyping, and research into epithelial cell differentiation and tumor origin. Validated for both manual and automated IHC platforms, the CK5 antibody is available in concentrated and ready-to-use formats, offering flexibility for both clinical and research laboratories. Its reproducible performance and lot-to-lot consistency make it a trusted choice for histopathologists and researchers alike. This antibody is a valuable tool in panels used for distinguishing between luminal and basal phenotypes in breast cancer, and for identifying squamous differentiation in tumors of the lung, cervix, head and neck, and skin. Key Features: Clone: EP1601Y Host Species: Rabbit Target: Cytokeratin-5 (CK5) Applications: Immunohistochemistry (IHC) on FFPE tissues Localization: Cytoplasmic Reactivity: Human Formulations: Available in both concentrated and ready-to-use Use Cases: Basal-like breast cancer, squamous cell carcinoma, epithelial tumor typing Compatibility: Suitable for manual and automated staining platforms Quality Control: Batch-tested for specificity, sensitivity, and reproducibility Ideal for diagnostic pathology and oncology research, the CK5 Rabbit Monoclonal Antibody (Clone EP1601Y) delivers dependable results for identifying basal epithelial markers, enhancing the precision of tumor classification and clinical interpretation.
EP1601Y
EP1601Y reacts to human Cytokeratin-4
A peptide corresponding to the C-terminus of human CK5(Cytokeratin-5)
Immunohistochemistry (IHC) Western Blot (WB)
Human
None
Research Use Only
Stable for 1 Year at -20.0°C from date of receipt.
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
