Cytomegalovirus (CMV)

Product Overview

The CMV antibody, clone 8B1.2/1G5.2/2D4.2, is a mouse monoclonal antibody cocktail specifically designed to detect cytomegalovirus (CMV) immediate early and early antigens in infected cells. This antibody blend comprises three distinct monoclonal clones—8B1.2, 1G5.2, and 2D4.2—each targeting different epitopes of CMV proteins, ensuring high sensitivity and broad reactivity across various CMV strains. Produced in mice, this monoclonal mixture is commonly used in immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded tissues to identify CMV-infected cells, particularly in clinical samples from immunocompromised patients where CMV reactivation is a concern. The antibody is especially useful for detecting CMV in tissue biopsies from organs such as the gastrointestinal tract, lungs, and retina. Its strong specificity and ability to recognize both early and immediate early antigens make it a reliable diagnostic tool for confirming CMV infection in both research and pathology laboratories.