CPS1 / Carbamoyl-Phosphate Synthetase 1 (Hepatic Mitochondrial Marker); Clone CPS1/1022 is a monoclonal antibody specifically developed to detect Carbamoyl-Phosphate Synthetase 1 (CPS1), a mitochondrial enzyme primarily expressed in hepatocytes and essential for the urea cycle. Clone CPS1/1022 provides strong and specific cytoplasmic and mitochondrial staining in formalin-fixed, paraffin-embedded (FFPE) tissue sections, making it a reliable marker for hepatocellular differentiation. This antibody is widely used in diagnostic pathology to distinguish hepatocellular carcinoma (HCC) from metastatic tumors of non-hepatic origin, due to its high specificity for liver tissue. Its robust staining pattern aids in accurate tumor classification and diagnosis, supporting clinical decision-making. The antibody’s concentrated format allows flexible dilution and protocol optimization to suit diverse laboratory workflows. Clone CPS1/1022 is an essential reagent in both clinical and research settings focused on liver pathology and mitochondrial function.
Mouse
Recombinant human CPS1 protein
CPS1/1022
IgG1
Human and Dog. Others not known.
HeLa cells. Liver or Hepatocellular Carcinoma (HCC).
This antibody recognizes a protein of 165kDa, identified as carbamoyl phosphate synthetase 1 (CPS1).
Finely granular cytoplasmic