Product Overview

Cytochrome c (Mitochondrial Marker); Clone 7H8.2C12 (Concentrate) is a monoclonal antibody specifically designed to detect Cytochrome c, a key mitochondrial protein involved in the electron transport chain and apoptosis. Clone 7H8.2C12 provides strong and specific cytoplasmic and mitochondrial staining in formalin-fixed, paraffin-embedded (FFPE) tissue sections, making it an essential tool for immunohistochemical analysis of mitochondrial integrity and function. This antibody is widely used in research and diagnostic pathology to study mitochondrial distribution, detect mitochondrial damage, and investigate apoptotic pathways in various diseases, including neurodegenerative disorders and cancers. The concentrated format allows for flexible dilution and optimization according to laboratory protocols. With its high specificity and robust staining pattern, Clone 7H8.2C12 serves as a reliable marker for mitochondrial localization and function in both clinical and research settings.

Specifications

Species

Mouse

Immunogen

Synthetic peptides corresponding to amino acids 1-80, 81-104 and 66-104 of pigeon cytochrome c.

Clone

7H8.2C12

Isotype

IgG2b, kappa

Species Reactivity

Human, Mouse, Rat, Horse, Dog, Pigeon, Frog, and Drosophila. Others not known.

Positive Control

K-562, HL-60, Jurkat, NIH3T3, or PC-3 cells. Cardiac muscle.

Specificity

This antibody recognizes an epitope within amino acids 93-104 of pigeon cytochrome c.

Cellular Localization

Cytoplasmic

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G0359RP