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Cytokeratin

CAM 5.2/Mouse/Monoclonal

GeneBioSolution Cytokeratin Antibody. GeneBio’s mouse monoclonal antibody recognizes Cytokeratin, a family of water-insoluble intracytoplasmic structural proteins that are the dominant intermediate filament proteins of epithelial and hair forming cells that are also present in epithelial tumors.

Anti-Cytokeratin (CAM 5.2) reagent has a primary reactivity with human keratin proteins that correspond to Moll`s peptides #7 and #8, MW 48 and 52 kDa, respectively. Cytokeratin 7 and 8 are present on secretory epithelia of normal human tissue but not on stratified squamous epithelium. Anti-Cytokeratin (CAM 5.2) stains most epithelial-derived tissue, including liver, renal tubular epithelium, and hepatocellular and renal cell carcinomas. Anti-Cytokeratin (CAM 5.2) may not react with some squamous cell carcinomas.

Specifications

Species Reactivity

Humans; others not tested

Known Applications

Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As

Buffer with protein carrier and preservative

Storage

Store at 2ºC to 8ºC

Control

Ovarian carcinoma

Visualization

Cytoplasmic

Isotype

IgG2a /κ

Immunogen

Purified human Keratin 8

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G2018RP