Cytokeratin 10 (Suprabasal Epithelial Marker); Clone KRT10/844 (Concentrate) is a monoclonal antibody specifically designed to detect Cytokeratin 10, a type I intermediate filament protein predominantly expressed in the suprabasal layers of keratinized stratified squamous epithelia. Clone KRT10/844 provides strong and specific cytoplasmic staining in formalin-fixed, paraffin-embedded (FFPE) tissue sections, making it a reliable tool for immunohistochemical analysis. This antibody is particularly useful for identifying and characterizing normal epidermal differentiation, as well as keratinizing squamous cell carcinomas and other skin-related pathologies. Its expression pattern helps differentiate between keratinizing and non-keratinizing epithelial lesions, contributing to accurate tumor classification and diagnostic evaluation. The concentrated format of Clone KRT10/844 allows for flexible dilution and protocol optimization, making it suitable for both research and clinical pathology applications.
Mouse
Recombinant human KRT10 protein
KRT10/844
IgG1, kappa
Human and Mouse. Others not known.
A431, HeLa, MCF7 cells or Esophagus.
This antibody recognizes a protein of 56.5kDa, identified as cytokeratin 10 (CK10).
Cytoplasmic