Product Overview
Clone: AE20
Cytokeratin 10 (Suprabasal Epithelial Marker); Clone AE20 (Concentrate) is a monoclonal antibody specifically developed to detect Cytokeratin 10, a type I intermediate filament protein predominantly expressed in the suprabasal layers of keratinized stratified epithelia, such as the epidermis. Clone AE20 provides strong and specific immunoreactivity in formalin-fixed, paraffin-embedded (FFPE) tissue sections, making it a valuable tool for immunohistochemical analysis in both clinical diagnostics and research. This antibody is particularly useful for studying epidermal differentiation and for identifying squamous cell carcinomas, where CK10 expression can aid in tumor subtyping and differentiation assessment. The concentrated format allows for flexible dilution and protocol optimization depending on laboratory needs. Clone AE20 is especially helpful in distinguishing keratinizing from non-keratinizing epithelial lesions, contributing to accurate histopathological evaluation and diagnostic decision-making.
