Product Overview
Clone: E3 (Ks17.E3)
Cytokeratin 17 (KRT17) (Basal Epithelial Marker); Clone E3 (Ks17.E3) is a monoclonal antibody specifically designed to detect Cytokeratin 17, a type I intermediate filament protein predominantly expressed in basal epithelial cells and certain progenitor or stem-like cell populations. Clone E3 (Ks17.E3) exhibits strong and specific immunoreactivity in formalin-fixed, paraffin-embedded (FFPE) tissue sections, making it a valuable tool for immunohistochemical applications in both research and diagnostic pathology. Cytokeratin 17 serves as a marker for basal cells in stratified epithelia and is often upregulated in various squamous cell carcinomas and other epithelial malignancies. This antibody aids in the identification and classification of tumors with basal-like features, including subsets of breast, lung, and skin cancers. The specificity and robust staining pattern of Clone E3 facilitate differentiation of basal epithelial-derived tumors from other neoplasms, supporting accurate diagnosis and contributing to a better understanding of tumor biology.
