The Cytokeratin 19 (CK19) Mouse Monoclonal Antibody, Clone A53-B/A2.26, is a highly specific and reliable antibody designed for the detection of CK19, a low-molecular-weight keratin expressed in the epithelial cells of various tissues. CK19 plays a crucial role in the structural integrity of epithelial cells and is commonly used as a diagnostic marker in immunohistochemistry (IHC) for identifying epithelial-derived tumors, including carcinomas of the liver, pancreas, lung, breast, and thyroid. Clone A53-B/A2.26 is widely recognized for its strong cytoplasmic staining with excellent specificity and low background, making it a valuable tool for pathologists in differentiating epithelial tumors from other neoplasms. This antibody is extensively validated for use on formalin-fixed, paraffin-embedded (FFPE) tissue sections, ensuring compatibility with routine clinical pathology workflows and research applications. Ideal for both manual and automated IHC platforms, the CK19 antibody provides consistent and reproducible results, aiding in tumor classification, prognostic evaluation, and cancer research. Its application extends to the identification of circulating tumor cells and cancer stem cell populations in various carcinomas, supporting advanced oncological studies. Key Features: Clone: A53-B/A2.26 Host: Mouse Monoclonal Target Protein: Cytokeratin 19 (CK19) Applications: Immunohistochemistry (IHC) on FFPE tissues Localization: Cytoplasmic Species Reactivity: Human Use Cases: Detection of epithelial tumors, carcinoma diagnostics, tumor typing Formulations: Available in concentrated and ready-to-use formats Compatibility: Suitable for manual and automated IHC staining systems Quality Assurance: Lot-to-lot consistency and validated specificity This Cytokeratin 19 Mouse Monoclonal Antibody (Clone A53-B/A2.26) is an essential reagent for clinical laboratories and research institutions focusing on epithelial tumor detection and characterization. It ensures precise immunohistochemical identification of CK19, facilitating accurate diagnosis and improved patient management.
Mouse
IgG
Affinity purification
Store at -20℃. Avoid freeze / thaw cycles
43kDa
44kDa
SMab Recombinant Monoclonal Antibody
WB,IHC-P,IF/ICC,ELISA
Human
GR2811
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Cytokeratin 19 (KRT19) (KRT19) (P08727).
Cytoplasm.