RA0173-C.5

Product Overview

Clone: H1

Cytokeratin 8 (KRT8); Clone H1 (Concentrate) is a monoclonal antibody developed to specifically recognize Cytokeratin 8, a type II intermediate filament protein commonly expressed in simple epithelial cells and a variety of epithelial tumors. Clone H1 exhibits high specificity and strong immunoreactivity in formalin-fixed, paraffin-embedded (FFPE) tissue sections, making it an effective tool for immunohistochemical analysis. It is particularly useful in the detection and classification of carcinomas originating from organs such as the liver, pancreas, and gastrointestinal tract. The concentrated format of Clone H1 allows for flexible dilution and customization to meet individual laboratory protocols and diagnostic needs. This antibody is widely employed in both clinical and research settings to aid in the differentiation of epithelial neoplasms from non-epithelial lesions, supporting accurate tumor diagnosis and histopathological evaluation.

Specifications

Species

Mouse

Immunogen

Cytoskeleton preparation containing cytokeratin 8

Clone

H1

Isotype

IgG1

Species Reactivity

Human, Rat, Zebrafish. Others not known.

Positive Control

MCF-7 or A431 cells. Skin, colon, lung, or breast carcinoma.

Specificity

Anti-CK8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against CK8, CK18 and CK19).

Cellular Localization

Cytoplasmic

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G0173RP