Cytokeratin Antibody (Mouse Monoclonal)

Cytokeratin Antibody (Mouse Monoclonal)

The Cytokeratin Antibody (Mouse Monoclonal) Clone 35betaH11 is a highly specific antibody designed for the detection of Cytokeratin 8 (CK8), a critical protein in the intermediate filament network of epithelial cells. This monoclonal antibody is particularly useful for immunohistochemistry (IHC) applications, offering precise and reliable detection of CK8 in formalin-fixed, paraffin-embedded (FFPE) tissue sections. Clone 35betaH11 is optimized for use in diagnostic pathology, providing significant utility in the identification and classification of various epithelial cell types and carcinomas. Key Features: Clone: 35betaH11 Host Species: Mouse Application: Immunohistochemistry (IHC) Reactivity: Specific to Cytokeratin 8 (CK8) Formulation: Available in convenient aliquot sizes (3.0 ml, 6.0 ml) Validated in: FFPE tissue samples Product Benefits: High Specificity: Clone 35betaH11 is specifically developed to bind to Cytokeratin 8, a marker commonly expressed in epithelial tissues such as the lung, breast, and liver. Reliable Performance: This antibody ensures consistent staining patterns with minimal background interference, making it ideal for tumor classification and prognostic evaluation. Enhanced Sensitivity: The monoclonal antibody offers high-affinity binding, ensuring strong cytoplasmic staining, even at low expression levels of CK8. Wide Application Range: Perfect for diagnostic and research applications, including studies related to epithelial differentiation, metastasis, and tumorigenesis. Optimized for IHC: Ideal for formalin-fixed, paraffin-embedded tissue samples, making it suitable for both research and clinical settings. Applications: Immunohistochemistry (IHC): This antibody is the preferred choice for CK8 detection in FFPE tissue sections. Tumor Profiling: Useful in the classification of carcinomas, particularly in the differentiation of epithelial tumors from mesenchymal tumors. Diagnostic Pathology: Assists pathologists in diagnosing various epithelial-origin cancers, including breast, lung, and liver carcinomas. Research Studies: Used to study epithelial differentiation, cancer progression, and other cell signaling pathways related to cytokeratin expression. Target Information: Target: Cytokeratin 8 (CK8) Molecular Weight: ~54 kDa Gene: KRT8 Cellular Localization: Cytoplasm (in epithelial cells) Technical Specifications: Host: Mouse Clone: 35betaH11 Isotype: IgG1 Conjugates: Available in various conjugated formats such as HRP or FITC for easy visualization and detection in IHC. Form: Liquid, stable under standard storage conditions. Why Choose Cytokeratin 8 Antibody Clone 35betaH11? This monoclonal antibody is an indispensable tool for researchers and clinicians working in the field of epithelial cancer diagnostics. Its specificity and high-quality performance make it a go-to choice for studies involving CK8-expressing tissues, enabling accurate, reproducible results for tissue profiling, cancer classification, and epithelial tumor studies. Conclusion: The Cytokeratin Antibody (Mouse Monoclonal) Clone 35betaH11 offers exceptional specificity and sensitivity for the detection of Cytokeratin 8, making it an invaluable tool in both diagnostic and research settings. Whether for tumor classification, cancer studies, or epithelial cell research, this antibody ensures reliable, high-quality results that meet the needs of advanced histopathology and molecular biology applications.