Cytokeratin
CAM 5.2/Mouse/Monoclonal
GeneBioSolution Cytokeratin Antibody. GeneBio’s mouse monoclonal antibody recognizes Cytokeratin, a family of water-insoluble intracytoplasmic structural proteins that are the dominant intermediate filament proteins of epithelial and hair forming cells that are also present in epithelial tumors.
Anti-Cytokeratin (CAM 5.2) reagent has a primary reactivity with human keratin proteins that correspond to Moll`s peptides #7 and #8, MW 48 and 52 kDa, respectively. Cytokeratin 7 and 8 are present on secretory epithelia of normal human tissue but not on stratified squamous epithelium. Anti-Cytokeratin (CAM 5.2) stains most epithelial-derived tissue, including liver, renal tubular epithelium, and hepatocellular and renal cell carcinomas. Anti-Cytokeratin (CAM 5.2) may not react with some squamous cell carcinomas.