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Desmin Antibody (Rabbit Monoclonal)

The Desmin Antibody (Rabbit Monoclonal, Clone EP15) is a premium-quality antibody developed by GeneBioSolution for immunohistochemistry (IHC) applications on formalin-fixed, paraffin-embedded (FFPE) tissues. Desmin is a muscle-specific, type III intermediate filament protein that plays a key role in maintaining the structural integrity of muscle cells. This antibody provides sensitive and specific detection of Desmin, producing strong cytoplasmic staining in skeletal, cardiac, and smooth muscle tissues with minimal background. The EP15 clone is widely validated in diagnostic pathology and is a trusted marker for the identification of muscle differentiation. In clinical pathology, Desmin EP15 is an essential tool in the diagnosis and classification of sarcomas, rhabdomyosarcomas, and leiomyosarcomas, as well as in distinguishing muscle-origin tumors from non-muscle neoplasms. Its robust performance makes it an important marker for both clinical diagnostics and translational research in oncology. GeneBioSolution ensures that all antibodies, including Desmin EP15, undergo stringent quality control, guaranteeing high specificity, reproducible staining, and lot-to-lot consistency. Optimized for both manual and automated IHC platforms, this antibody delivers reliable results across diverse laboratory settings. Key Features Clone: EP15 (Rabbit Monoclonal) Application: IHC on FFPE tissues Target Protein: Desmin – muscle-specific intermediate filament Diagnostic Utility: Sarcomas, rhabdomyosarcomas, leiomyosarcomas, tumor differentiation Performance: High specificity, consistent staining, low background

Specifications

Clone Name

GRM322

Specificity

GRM322 reacts to Histone H3 only when modified by both methylation at lysine 9 and acetylation at lysine 14 (K9me2/K14ac). No cross reactivity with monomethylated Lysine 9 (K9me1), dimethylated Lysine 9 (K9me2), trimethylated Lysine 9 (K9me3), or acetylated Lysine 9/14 only, in histone H3.

Immunogen

A dimethyl-peptide corresponding to dimethyl-Histone H3 (Lys9) and an acetyl-peptide corresponding to Acetyl-Histone H3 (Lys14)

Application

Western Blot (WB) Multiplex

Species Reactivity

Human

Conjugate

None

Intended Use

Research Use Only

Storage and Stability

Stable for 1 Year at -20.0°C from date of receipt.

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G1207RP