The Double Stranded DNA (dsDNA) Antibody [Clone DSD/958] is a high-affinity mouse monoclonal antibody developed for the specific detection of native dsDNA in human cells and tissues. It is an excellent nuclear marker used in a variety of applications including immunohistochemistry (IHC), immunocytochemistry (ICC), enzyme-linked immunosorbent assays (ELISA), and flow cytometry. Clone DSD/958 is particularly valuable in autoimmune disease research, especially for detecting anti-dsDNA antibodies, which are a hallmark of systemic lupus erythematosus (SLE). It demonstrates strong and selective nuclear localization, making it ideal for assessing nuclear morphology, DNA integrity, and cellular proliferation status.
Mouse
Nuclei of Burkitt's cells
DSD/958
IgG2b / Kappa
Human
Jurkat or HeLa cells. Tonsil or Colon., Raji
This monoclonal antibody is part of a new panel of reagents, which recognizes subcellular organelles or compartments of human cells.
N/A