The Double Stranded DNA (dsDNA) Antibody [Clone SPM603] is a high-affinity mouse monoclonal antibody specifically designed for the detection of native double-stranded DNA (dsDNA) in human tissues and cells. It is an effective nuclear marker and plays a significant role in both research and diagnostic pathology, particularly for identifying autoimmune conditions such as systemic lupus erythematosus (SLE). SPM603 demonstrates strong nuclear staining with minimal background and is ideal for a variety of applications including immunohistochemistry, immunocytochemistry, ELISA, and flow cytometry. Its ability to bind native dsDNA makes it suitable for evaluating nuclear integrity, cell proliferation, and autoantibody interactions.
Mouse
Nuclei of Burkitt's cells
SPM603
IgG3 / Kappa
Human
Tonsil
This monoclonal antibody is part of a new panel of reagents, which recognizes subcellular organelles or compartments of human cells.
Nuclear