Double Stranded DNA (dsDNA) (Nuclear Marker)

The Double Stranded DNA (dsDNA) Antibody [Clone SPM603] is a high-affinity mouse monoclonal antibody specifically designed for the detection of native double-stranded DNA (dsDNA) in human tissues and cells. It is an effective nuclear marker and plays a significant role in both research and diagnostic pathology, particularly for identifying autoimmune conditions such as systemic lupus erythematosus (SLE). SPM603 demonstrates strong nuclear staining with minimal background and is ideal for a variety of applications including immunohistochemistry, immunocytochemistry, ELISA, and flow cytometry. Its ability to bind native dsDNA makes it suitable for evaluating nuclear integrity, cell proliferation, and autoantibody interactions.

Specifications

Species

Mouse

Immunogen

Nuclei of Burkitt's cells

Clone

SPM603

Isotype

IgG3 / Kappa

Species Reactivity

Human

Positive Control

Tonsil

Specificity

This monoclonal antibody is part of a new panel of reagents, which recognizes subcellular organelles or compartments of human cells.

Cellular Localization

Nuclear

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G0632RP