The E-Cadherin Antibody (Rabbit Monoclonal, Clone EP700Y) is a high-quality antibody from GeneBioSolution, specifically developed for immunohistochemistry (IHC) applications on formalin-fixed, paraffin-embedded (FFPE) tissues. E-Cadherin, also known as Cadherin-1 (CDH1), is a calcium-dependent adhesion molecule that plays a crucial role in epithelial cell adhesion, tissue integrity, and tumor suppression. This antibody provides sensitive and specific detection of E-Cadherin, delivering strong membranous staining with minimal background. The EP700Y clone has been widely validated for its robust performance in routine diagnostics and advanced research, making it a trusted marker for the evaluation of epithelial tumors and carcinomas. In clinical pathology, loss or reduction of E-Cadherin expression is associated with epithelial-to-mesenchymal transition (EMT) and progression of several cancers, including breast, gastric, prostate, ovarian, and colorectal carcinomas. Therefore, E-Cadherin IHC staining is highly valuable in tumor classification, prognosis, and cancer research. All GeneBioSolution antibodies undergo rigorous quality control and validation, ensuring lot-to-lot consistency, reproducible IHC performance, and compatibility with automated stainers.
Humans; others not tested
Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Buffer with protein carrier and preservative
Store at 2ºC to 8ºC
Skin or breast carcinoma
Membrane
IgG
Purified His-tagged CDH1 protein
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
