The EGFR Antibody (Rabbit Monoclonal, Clone EP22) is a high-affinity antibody developed by GeneBioSolution for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) tissues. EGFR (Epidermal Growth Factor Receptor), also known as HER1 or ErbB1, is a transmembrane receptor tyrosine kinase that plays a pivotal role in cell growth, differentiation, and survival. This antibody provides sensitive and specific detection of EGFR expression, delivering strong membranous staining with minimal background. The EP22 clone is widely validated and recognized for its reliability in both diagnostic pathology and cancer research, making it an essential tool in the evaluation of solid tumors and targeted therapy eligibility. In clinical applications, EGFR immunostaining is particularly valuable in the assessment of non-small cell lung carcinoma (NSCLC), colorectal carcinoma, breast carcinoma, and glioblastomas. Overexpression or mutation of EGFR is associated with tumor progression, poor prognosis, and responsiveness to targeted therapies such as tyrosine kinase inhibitors (TKIs). GeneBioSolution ensures that all antibodies, including EGFR EP22, undergo rigorous quality control to guarantee lot-to-lot consistency, strong staining performance, and compatibility with automated IHC platforms.
Humans; others not tested
Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Buffer with protein carrier and preservative
Store at 2ºC to 8ºC
Lung adenocarcinoma
Membranous
IgG
Recombinant fragment of human EGFR protein (around aa 344-492)
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
