The EGFR Rabbit Monoclonal Antibody [Clone GFR450] provides high specificity and sensitivity for detecting Epidermal Growth Factor Receptor (EGFR / HER1 / ErbB1) in human tissues. EGFR is a transmembrane receptor tyrosine kinase involved in the regulation of cell growth, survival, and differentiation, and is a well-established biomarker in epithelial cancers. Clone GFR450, generated using rabbit monoclonal technology, offers superior signal-to-noise ratio and enhanced performance in formalin-fixed, paraffin-embedded (FFPE) tissues, making it a powerful tool for use in cancer diagnostics, target validation, and research studies involving EGFR expression.
Mouse
Recombinant human EGFR protein
GFR450
IgG2a, kappa
Human. Others not known.
A431 cells. Breast or bladder cancer.
This antibody recognizes a protein of 170kDa, identified as EGFR.
Cell surface