The EGFR Mouse Monoclonal Antibody [Clone SPM622] is designed to specifically detect Epidermal Growth Factor Receptor (EGFR / HER1 / ErbB1), a key transmembrane tyrosine kinase receptor involved in cellular proliferation and survival. Clone SPM622 demonstrates strong membranous and cytoplasmic staining in EGFR-expressing tissues and is optimized for use in formalin-fixed, paraffin-embedded (FFPE) specimens. This antibody is valuable in the evaluation of EGFR expression in various tumors, including non-small cell lung cancer (NSCLC), colorectal carcinoma, and head and neck cancers, making it a useful tool in diagnostic pathology and targeted therapy decision-making.
Mouse
Human EGFR purified from A431 cells.
SPM622
IgG2a, kappa.
Reacts with human. Others not known.
A431 cells. Placenta, breast, colon, or bladder cancer.
This monoclonal antibody recognizes a protein of 170kDa, identified as EGFR.
Cell surface.