Fighting Cancer, One Slide at a Time

RA0196-C.5 (1)

Ep-CAM / CD326 (Epithelial Marker)

The Ep-CAM / CD326 Mouse Monoclonal Antibody [Clone MOC-31] is a widely validated tool for identifying Epithelial Cell Adhesion Molecule (Ep-CAM / CD326), a membrane glycoprotein expressed on most epithelial tissues and carcinomas. Clone MOC-31 is known for producing strong membranous staining in epithelial-derived cells and tumors, with minimal cross-reactivity with mesenchymal or hematopoietic cells. This antibody is extensively used for differentiating carcinomas from mesotheliomas, identifying metastatic adenocarcinomas, and detecting circulating tumor cells (CTCs) in clinical and research settings.

Specifications

Species

Mouse

Immunogen

Neuraminidase treated GLS-1 human small cell lung carcinoma cells

Clone

MOC-31

Isotype

IgG1, kappa

Species Reactivity

Human. Does not react with Rat. Others not known.

Positive Control

HT29 cells or breast tumor.

Specificity

The epitope of this antibody is located in the first EGF-like repeat domain (EGF1) between amino acids 27-59 of Ep-CAM.

Cellular Localization

Cell surface

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G0196RP