Galectin-3 Antibody (Rabbit Monoclonal)

Galectin-3-antibody

The Galectin-3 Antibody (Rabbit Monoclonal, Clone EP412) from GeneBioSolution is a high-quality antibody designed for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) tissues. Galectin-3 is a β-galactoside-binding lectin involved in cell adhesion, proliferation, apoptosis, immune regulation, and tumor progression. This antibody provides sensitive and specific cytoplasmic and nuclear staining of Galectin-3, with minimal background. The EP412 clone is widely used in diagnostic pathology, particularly in the evaluation of thyroid lesions. Galectin-3 positivity supports the diagnosis of thyroid carcinomas (especially papillary and follicular thyroid carcinoma) and helps distinguish malignant thyroid tumors from benign nodules. Beyond thyroid pathology, Galectin-3 is expressed in a variety of malignant tumors including colorectal, breast, lung, and gastric cancers, making it a valuable marker for both diagnostic and research applications. All GeneBioSolution antibodies undergo strict validation and quality control, ensuring lot-to-lot consistency, reproducible staining, and compatibility with both manual and automated IHC platforms. Clinical & Research Applications Diagnostic aid in thyroid carcinoma vs. benign thyroid nodules Marker of tumor progression and metastasis Evaluation of Galectin-3 expression in breast, lung, gastric, and colorectal carcinomas Research on cell adhesion, apoptosis, and immune modulation Key Features Clone: EP412 (Rabbit Monoclonal) Application: Immunohistochemistry (IHC) on FFPE tissues Target Protein: Galectin-3 – β-galactoside-binding lectin Diagnostic Utility: Thyroid carcinoma, colorectal cancer, breast and lung tumors Performance: Strong cytoplasmic and nuclear staining, high sensitivity, reproducible results