The GATA3 antibody [L50-823] is a monoclonal antibody that targets GATA3, a transcription factor critical for the development and function of various tissues, including the mammary gland, thymus, and urogenital system. GATA3 plays a significant role in regulating T-cell differentiation and is widely expressed in luminal epithelial cells of the breast and in various other cell types. The [L50-823] clone is commonly used in immunohistochemistry (IHC) and flow cytometry for the identification of GATA3-positive cells, particularly in breast cancer diagnosis, where it serves as a marker for luminal subtype tumors. It is also used in the diagnosis of urothelial carcinomas and other tumors with GATA3 expression. This antibody is valuable in clinical oncology for determining the origin of metastatic tumors and in research related to cell differentiation, cancer biology, and immune system function.
Mouse
Monoclonal
L50-823
IgG1
WB, IHC-P
Human, Mouse
Store at 4ºC.
Conserved peptide between the GATA transactivation and DNA-binding domain of human.
