The GATA-3 Antibody (Mouse Monoclonal) from GeneBioSolution is a high-quality antibody optimized for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) tissues. GATA-3 is a zinc finger transcription factor essential for T-cell development, immune regulation, and epithelial differentiation. This antibody provides sensitive and specific nuclear staining of GATA-3, making it a valuable biomarker in both diagnostic pathology and cancer research. In routine diagnostics, GATA-3 is widely used as an immunohistochemical marker for breast carcinoma, urothelial carcinoma, and T-cell lymphomas, aiding in differential diagnosis and tumor classification. Beyond diagnostic utility, GATA-3 also plays a critical role in immune system regulation and epithelial biology, making it useful in translational research and studies of tumor progression, metastasis, and immunotherapy response. All GeneBioSolution antibodies undergo rigorous quality control and validation, ensuring lot-to-lot consistency, strong nuclear staining, and reproducible results on both manual and automated IHC platforms. Clinical & Research Applications Diagnostic marker for breast carcinoma and urothelial carcinoma Identification of T-cell lymphomas and other hematologic malignancies Research into immune regulation, epithelial differentiation, and transcriptional control Useful in tumor classification, prognosis, and cancer biomarker studies Key Features Type: Mouse Monoclonal Antibody Application: Immunohistochemistry (IHC) on FFPE tissues Target Protein: GATA-3 – transcription factor Diagnostic Utility: Breast carcinoma, urothelial carcinoma, T-cell lymphomas Performance: Strong nuclear staining, high specificity, reproducible results
Mouse
Monoclonal
L50-823
IgG1
WB, IHC-P
Human, Mouse
Store at 4ºC.
Conserved peptide between the GATA transactivation and DNA-binding domain of human.