The GATA-3 Antibody (Rabbit Monoclonal) from GeneBioSolution is a high-performance antibody optimized for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) tissues. GATA-3 is a zinc finger transcription factor critical for T-cell development, immune regulation, and epithelial differentiation. This antibody provides sensitive and specific nuclear staining of GATA-3 with superior affinity compared to conventional mouse monoclonals. The rabbit monoclonal format enhances signal strength, antigen recognition, and lot-to-lot consistency, making it a reliable biomarker in both diagnostic pathology and translational research. In clinical diagnostics, GATA-3 is a widely used marker for breast carcinoma, urothelial carcinoma, and T-cell lymphomas, supporting tumor classification and differential diagnosis. Its consistent nuclear staining pattern makes it a trusted marker for pathologists in routine IHC panels. Beyond oncology, GATA-3 is also a key regulator in immune biology and epithelial tissue development, providing research applications in immunology, cancer progression, and targeted therapy studies. All GeneBioSolution antibodies undergo rigorous quality control and validation, ensuring high reproducibility, compatibility with automated IHC stainers, and strong nuclear staining performance. Clinical & Research Applications Diagnostic marker for breast carcinoma and urothelial carcinoma Detection of T-cell lymphomas and hematologic malignancies Research on immune regulation, epithelial differentiation, and transcriptional control Biomarker for cancer classification, prognosis, and immunotherapy response
GRM482
This antibody reacts to human GATA3 (Trans-acting T-cell-specific transcription factor GATA-3) (GATA-binding factor 3).
A peptide corresponding to Human GATA3
Immunohistochemistry (IHC); Western Blot (WB)
Human, Mouse, Rat
None
Research Use Only
Stable for 1 Year at -20.0°C from date of receipt.