The GFAP Mouse Monoclonal Antibody (Clone SPM248) is a highly specific reagent designed for the detection of Glial Fibrillary Acidic Protein (GFAP), a type III intermediate filament protein expressed primarily by astrocytes in the central nervous system (CNS). This clone offers reliable and robust immunostaining in various applications, including immunohistochemistry of formalin-fixed, paraffin-embedded (FFPE) tissues. Clone SPM248 is particularly useful in identifying astrocytic differentiation in tumors, detecting gliosis, and studying neural development or injury responses.
Mouse
GFAP isolated from pig spinal cord
SPM248
IgG1 / Kappa
Chicken, Cow, Human, Mouse, Pig, Rabbit, Rat
T98G cells (FACS). Brain lysate (WB). Brain or Astrocytoma (IHC).
This MAb recognizes a protein of ~50kDa which is identified as Glial Fibrillary Acidic Protein (GFAP).
Cytoplasm