The G-CSF Mouse Monoclonal Antibody [Clone SPM468] is a high-affinity, specific antibody designed for the detection of Granulocyte Colony-Stimulating Factor (G-CSF / CSF3), a key regulator of neutrophil development, function, and survival. G-CSF is primarily secreted by macrophages, endothelial cells, and fibroblasts in response to immune stress or inflammation. Clone SPM468 is validated for use in formalin-fixed, paraffin-embedded tissues and is ideal for both research and diagnostic studies, especially those focused on hematologic malignancies, inflammatory disorders, and tumor microenvironment dynamics.
Mouse
Nuclei from pokeweed mitogen stimulated human peripheral blood lymphocytes.
SPM468
IgG1
Reacts with human and macaque monkey. Others not known.
HL60 cells, tonsil, or lymph node.
This monoclonal antibody recognizes granulocyte-colony stimulating factor (G-CSF) in the cytoplasm of mature granulocytes.
Cytoplasmic