Granzyme B Antibody (Rabbit Monoclonal)

Granzyme B Antibody (Rabbit Monoclonal)

The Granzyme B Antibody (Rabbit Monoclonal, Clone EP230) from GeneBioSolution is a high-quality antibody validated for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) tissues. Granzyme B is a serine protease stored in the cytotoxic granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells, playing a central role in the induction of apoptosis in target cells. This antibody delivers sensitive and specific cytoplasmic staining of Granzyme B, enabling reliable detection of activated cytotoxic immune cells in tissue samples. The EP230 clone is particularly useful in oncology and immunology research, as well as in diagnostic pathology, to evaluate the cytotoxic immune response within tumors, viral infections, and immune-mediated disorders. In clinical practice, Granzyme B IHC can provide insights into tumor immune microenvironment, immunotherapy response, transplant rejection, and autoimmune diseases. GeneBioSolution ensures all antibodies undergo rigorous quality control and validation, guaranteeing lot-to-lot consistency, strong cytoplasmic staining, and reproducible results across both manual and automated IHC platforms. Clinical & Research Applications Detection of cytotoxic T cells and NK cells in FFPE tissues Immune profiling in cancer, viral infections, and autoimmune diseases Evaluation of tumor immune microenvironment and immunotherapy response Assessment of transplant rejection and immune activation