Fighting Cancer, One Slide at a Time

HBME-1

The GeneBio HBME-1 Antibody (Rabbit Monoclonal) is a highly sensitive and specific recombinant antibody designed for the detection of HBME-1, a well-established marker for mesothelial cells and epithelial tumors. HBME-1 is particularly valuable in distinguishing malignant mesothelioma from adenocarcinomas and is widely used in the diagnosis of thyroid malignancies, including papillary and follicular thyroid carcinoma. This antibody provides strong membranous and cytoplasmic staining patterns, delivering clear differentiation between benign and malignant lesions in immunohistochemistry (IHC). Its high specificity and minimal background make it an essential tool for surgical pathology and diagnostic workflows. Validated for use in IHC on formalin-fixed, paraffin-embedded (FFPE) tissues, the HBME-1 antibody has become a cornerstone in cancer pathology panels. Produced using advanced rabbit monoclonal technology, the GeneBio HBME-1 Antibody ensures superior sensitivity, reproducibility, and lot-to-lot consistency compared to traditional polyclonals. It is protein A affinity-purified and supplied in a stabilizing buffer (PBS with BSA, glycerol, and sodium azide) to guarantee purity and stability. Each vial is delivered at ~1 mg/mL concentration, shipped chilled, and recommended for storage at –20 °C, avoiding repeated freeze–thaw cycles. With its proven diagnostic value, high performance in IHC, and consistent quality, the GeneBio HBME-1 Antibody is the trusted choice for pathologists and researchers working in cancer diagnostics, particularly for mesothelioma, lung, and thyroid cancer investigations.

Specifications

Species Reactivity

Humans; others not tested

Known Applications

Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As

Buffer with protein carrier and preservative

Storage

Store at 2ºC to 8ºC

Control

Mesothelioma

Visualization

Cytoplasmic

Isotype

IgG1 /κ

Immunogen

A suspension of mesothelioma cells of human origin

Ordering Information

Format:

Volume:

  • Classification
  • RUO
  • Catalogue Number
  • G2233RP