The hCG-beta Antibody is a highly specific antibody designed to detect the beta subunit of human chorionic gonadotropin (hCG-beta), a hormone prominently produced during pregnancy and by certain trophoblastic tumors such as choriocarcinoma. This antibody is extensively used in immunohistochemistry (IHC) to accurately identify and localize hCG-beta expression in formalin-fixed, paraffin-embedded (FFPE) tissue sections. hCG-beta plays a crucial role as a biomarker for pregnancy, gestational trophoblastic diseases, and germ cell tumors. The antibody’s specificity allows for sensitive detection of trophoblastic cells, aiding in the diagnosis of choriocarcinoma, hydatidiform mole, and other hCG-secreting tumors. It also assists in distinguishing these tumors from other malignancies, improving diagnostic precision and guiding appropriate clinical management. Manufactured using advanced monoclonal antibody technology, this reagent delivers consistent performance with minimal background staining. Its strong cytoplasmic and membranous staining pattern enables clear visualization of hCG-beta positive cells, making it an essential tool for pathologists and researchers focused on reproductive health, oncology, and tumor biology. Target: Beta subunit of human chorionic gonadotropin (hCG-beta) Applications: Immunohistochemistry (IHC) on FFPE tissues Staining Pattern: Cytoplasmic and membranous Use Cases: Detection of pregnancy-related tissues Diagnosis of choriocarcinoma and trophoblastic tumors Identification of germ cell tumors secreting hCG Research in reproductive biology and oncology Advantages: High specificity, sensitive detection, reproducible results, minimal background staining
Mouse
Recombinant hCG beta protein
Rabbit Polyclonal
IgG1, kappa
Human. Others not known.
JAR or TT Cells. Placenta.
This monoclonal antibody reacts with a protein of 22kDa, identified as the beta subunit of hCG.
Cytoplasmic, secreted