The Heat Shock Protein 70 (HSP70) Antibody (Rabbit Monoclonal, Clone EP377) from GeneBioSolution is a premium-quality antibody validated for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) tissues. HSP70 is a highly conserved molecular chaperone involved in protein folding, protection against cellular stress, and regulation of apoptosis. This antibody provides sensitive and specific cytoplasmic and nuclear staining of HSP70 with minimal background. The EP377 clone is widely used in diagnostic pathology and cancer research for detecting stress responses in tumor cells, and it is particularly valuable in evaluating hepatocellular carcinoma, colorectal carcinoma, breast carcinoma, and other solid tumors. Overexpression of HSP70 is frequently associated with tumor progression, resistance to apoptosis, and poor prognosis, making it a useful biomarker for both diagnostic and prognostic purposes. In addition, HSP70 plays a key role in immunology and infectious disease research, where it contributes to cellular defense mechanisms against stress, heat shock, and toxic insults. All GeneBioSolution antibodies undergo rigorous validation and quality control, ensuring lot-to-lot consistency, reproducible IHC performance, and compatibility with both manual and automated staining platforms. Clinical & Research Applications Diagnostic aid in hepatocellular carcinoma, colorectal carcinoma, and breast cancer Marker for cellular stress response and apoptosis regulation Research on cancer biology, tumor progression, and treatment resistance Studies in infectious disease, neurodegeneration, and cellular stress physiology
Humans; others not tested
Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Buffer with protein carrier and preservative
Store at 2ºC to 8ºC
IgG
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
