Helicobacter Pylori

Product Overview

The Helicobacter pylori urease B antibody (polyclonal) is a laboratory reagent used to detect and study the urease B subunit of the Helicobacter pylori bacterium. This polyclonal antibody is typically produced by immunizing animals such as rabbits with purified or recombinant urease B protein, leading to the generation of a mixture of antibodies that recognize multiple epitopes on the target antigen. Urease B is a critical component of the urease enzyme complex, which enables H. pylori to survive in the acidic environment of the human stomach by breaking down urea to produce ammonia. The antibody is highly specific to the urease B subunit, which has a molecular weight of approximately 60 kDa. It is widely used in research applications such as Western blotting, enzyme-linked immunosorbent assay (ELISA), and immunohistochemistry (IHC) to detect, quantify, or localize H. pylori in various samples. This tool is especially valuable for studying the pathogenesis of H. pylori-related diseases and for developing diagnostic methods.