The HGAL Antibody (Mouse Monoclonal, Clone MRQ-45) from GeneBioSolution is a high-quality antibody optimized for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) tissues. HGAL (Human Germinal Center–Associated Lymphoma protein) is a B-cell–associated protein strongly expressed in germinal center B cells and certain lymphoid neoplasms. This antibody provides sensitive and specific cytoplasmic staining of HGAL, with minimal background. The MRQ-45 clone is particularly useful in the diagnosis of Hodgkin lymphoma and B-cell lymphomas, including follicular lymphoma and diffuse large B-cell lymphoma (DLBCL), where HGAL expression serves as a supportive biomarker. In pathology, HGAL is employed as part of an antibody panel with BCL6, CD10, and MUM1 to classify lymphomas and determine cell-of-origin subtypes. Beyond diagnostic use, HGAL is increasingly studied in B-cell biology, germinal center reactions, and lymphoma progression, making it a valuable antibody for both clinical and research applications. All GeneBioSolution antibodies undergo rigorous validation and quality control, ensuring lot-to-lot consistency, reproducible IHC results, and compatibility with manual and automated staining systems. Clinical & Research Applications Diagnostic aid in Hodgkin lymphoma, follicular lymphoma, and DLBCL Marker of germinal center B-cell origin Research into B-cell development, germinal center activity, and lymphoma progression Supports antibody panels for lymphoma classification and prognosis
Mouse
IgG
Affinity purification
Store at -20℃. Avoid freeze / thaw cycles
Recombinant Monoclonal Antibody
WB,IHC-P,IF/ICC,IP,ELISA
Human
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
