HSP60 (Heat Shock Protein 60)

The HSP60 Monoclonal Antibody [Clone LK1] is a mouse monoclonal antibody that specifically detects Heat Shock Protein 60 (HSP60), also known as HSPD1. HSP60 is a key mitochondrial chaperonin involved in the proper folding and assembly of mitochondrial proteins. Beyond its intracellular role, HSP60 is also implicated in immune activation, autoimmune diseases, and tumor progression, making it a versatile marker for both cellular stress and pathology research.

Specifications

Species

Mouse

Immunogen

Recombinant human HSP60 protein

Clone

LK1

Isotype

IgG1, kappa

Species Reactivity

Human, Mouse, Rat, Hamster, Sheep, Rabbit, Cow, Dog, Pig, Monkey, Chicken, Xenopus laevis, and Drosophila.

Positive Control

HeLa or HepG2 cells. Breast carcinoma. Synovial biopsies from patients with juvenile chronic arthritis. Synovial lining layer is strongly positive for HSP60.

Specificity

This antibody recognizes a 60kDa protein, identified as the heat shock protein 60 (HSP60).

Cellular Localization

Cytoplasmic