The Human Immunoglobulin M (IgM) Antibody (Rabbit Monoclonal) from GeneBioSolution is a premium-quality antibody optimized for immunohistochemistry (IHC) on formalin-fixed, paraffin-embedded (FFPE) tissues) and compatible with immunoassays. IgM is the first immunoglobulin produced in the primary immune response and plays a critical role in early defense against infections, complement activation, and immune regulation. This antibody provides sensitive and specific cytoplasmic staining of IgM in plasma cells, B lymphocytes, and other IgM-secreting cells, with minimal background. The rabbit monoclonal format offers higher affinity, reproducibility, and superior sensitivity compared to conventional polyclonals. In diagnostic pathology, IgM immunohistochemistry is essential for evaluating plasma cell disorders, B-cell lymphomas, and immunoglobulin subclass expression. It is commonly used in panels alongside IgG, IgA, and light chain antibodies (kappa and lambda) to assess clonality and subclass restriction. In research, IgM antibodies support studies on early immune responses, autoimmune diseases, and immunoglobulin biology, making them a valuable tool in both basic immunology and translational medicine. All GeneBioSolution antibodies undergo rigorous validation and quality control, ensuring lot-to-lot consistency, strong staining performance, and compatibility with manual and automated IHC platforms.
GRM117
GRM117 reacts to the heavy chain of human IgG1. GRM117 does not cross react to any other IgG subclasses (IgG2, IgG3, or IgG4), and shows no cross reactivity to IgM, IgA, IgD, IgE. GRM117 does not react to monkey (Cyno or Rhesus) IgG, mouse IgG, rat IgG, or goat IgG.
Peptide corresponding to the hinge region of Human IgG1.
Immunohistochemistry (IHC) Flow Cytometry (FC) Immunocytochemistry (ICC) ELISA
Human.
None
Research Use Only
Stable for 1 Year at -20.0°C from date of receipt.
At Genebiosolution, our commitment lies in crafting cutting-edge solutions for researchers, clinicians, and diagnostic laboratories seeking excellence in immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). With a focus on quality, reliability, and accuracy, our products empower advancements in molecular diagnostics and research methodologies.
